Bioinformatics

Bioinformatics is an area of computational science that has to do with the biological molecules sequence analysis. Bioinformatics generally refers to genes, DNA, RNA, or protein, and is particularly beneficial in comparing genes and other sequences in proteins and other sequences within an organism or between organisms, observing at evolutionary relationships between organisms, and using the patterns that occur across DNA and protein sequences to identify the functions.

Bioinformatics Courses

Required Elective Courses

2300361 INTRODUCTION TO MOLECULAR BIOTECHNOLOGY

Introduction to and history of molecular biotechnology; reviews on regulation of gene expression in prokaryotes and eukaryotes; principles and techniques in recombinant DNA technology; production of recombinant protein in prokaryotes and eukaryotes; mutagenesis, protein engineering and directed evolution; various applications of molecular biotechnology.

3(3-0-6) credits

2300362 BIOLOGICAL SEQUENCE ANALYSIS

Methods and algorithms for sequence alignment: pairwise sequence alignment, database similarity searching, multiple sequence alignment; profiles and Hidden Markov Models; gene finding and protein sequence analysis; processing of data obtained from DNA sequencers including assembly of raw data into a contiguous sequence, finding open reading frames and translating into amino acid sequences; sequence analysis tools used in recombinant DNA technology including restriction mapping, primer design, DNA cloning and mutagenesis; DNA, RNA and amino acid sequence analysis using publicly available web based tools.

3(2-2-5) credits

2305262 GENERAL GENETICS LABORATORY

Laboratory work emphasizing the principles of inheritance; experiments with microorganisms and an independent study of inheritance in Drosophila melanogaster and Zea mays; problems solving and discussion.

1(0-3-0) credit

Elective Courses

2300301 COMPUTER SKILLS IN BIOINFORMATICS

Data structures; file input and output; sequential statements; if statements; loop; arithmetic operations; shell scripts; basic Linux operating system commands for bioinformatics work.

3(2-3-4) credits

2310451  GENOMIC ANALYSIS FOR BIOTECHNOLOGY

Introduction to bioinformatics, using the internet and operating systems for working with databases, databases for biological research, retrieval of information and submitting sequences to the databases, sequence analysis including nucleotide and amino acid sequence alignments, database searching, phylogenetic analysis, predictive methods for gene structures and protein sequences, analysis and design of protein tertiary structure and nucleic acids, analysis of genome and gene expression in genomic scale.

3(2-2-8) credits

2310454  INTRODUCTION TO GENETIC ENGINEERING

Introduction to genetic engineering; working with nucleic acid; isolation of DNA/RNA, qualitative and qualitative measurement of nucleic acid, gel electrophoresis, enzymes in genetic engineering, PCR and RT-PCR, labeling and hybridization, DNA sequencing; cloning strategy; hosts, vectors, DNA digestion and ligation, transformation and transfection, screening and selection, expression of recombinant protein; gene expression analysis; essential bioinformatics; applications in gene expression analysis; essential bioinformatics; applications in genetic engineering.

2(0-6-2) credits

2310555  GENETIC ENGINEERING LABORATORY

Recombinant DNA technology; extraction, cutting and joining of DNA, transformation; screening of genes of interested genes.

2(0-6-2) credits